Pramipexole: new use for an old drug ? the potential use of pramipexole in the treatment of restless legs syndrome
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چکیده
منابع مشابه
Pramipexole: new use for an old drug – the potential use of pramipexole in the treatment of restless legs syndrome
Restless legs syndrome (RLS) is characterized by paraesthesias-dysesthesias and motor restlessness worsening at rest-in the evening, with at least temporary relief by activity. Its etiology is unknown, though it could be secondary to various conditions. It is well known, however, that dopamine plays a crucial role in the pathophysiology of RLS, as dopaminergic agonists achieve marked improvemen...
متن کاملLong-term treatment with pramipexole in restless legs syndrome.
The aim of the present study was to look at the long-term efficacy and side effects profiles of pramipexole in a large cohort of drug naïve patients with regard to dopaminergic medications. In all, 195 consecutive restless legs syndrome (RLS) patients who were prescribed pramipexole more than 1 year previously, agreed to undergo a telephone interview to assess both the efficacy and side effects...
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abstract nowadays, the science of decision making has been paid to more attention due to the complexity of the problems of suppliers selection. as known, one of the efficient tools in economic and human resources development is the extension of communication networks in developing countries. so, the proper selection of suppliers of tc equipments is of concern very much. in this study, a ...
15 صفحه اولLong-term use of pramipexole in the management of restless legs syndrome.
OBJECTIVE Few studies have examined the long-term use of dopamine agonists for restless legs syndrome (RLS). We report a cohort study of 50 patients initially prescribed pramipexole between 1998 and 2002. The objective was to determine duration of treatment, long-term efficacy, development of side effects and augmentation over an extended period. METHODS We performed a long-term analysis on a...
متن کاملRestless legs syndrome: differential diagnosis and management with pramipexole
Restless legs syndrome (RLS) is a condition characterized by discomfort at rest and urge to move focused on the legs. RLS may occur as an idiopathic, often hereditary condition (primary RLS), or in association with medical conditions (secondary RLS) including iron deficiency, uremia, and polyneuropathy. Current understanding of the pathophysiology of RLS points to the involvement of three inter...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2006
ISSN: 1176-6328
DOI: 10.2147/nedt.2006.2.4.393